[et_pb_section fb_built=”1″ fullwidth=”on” admin_label=”• Seção – CATEGORIA E TÍTULO •” _builder_version=”4.5.6″ _module_preset=”default” custom_css_main_element=”/* position: absolute;||top: 0;||left: 0;||z-index: 9;||width: 100%; */” global_module=”182″][et_pb_fullwidth_header title=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9jYXRlZ29yaWVzIiwic2V0dGluZ3MiOnsiYmVmb3JlIjoiIiwiYWZ0ZXIiOiLCJsaW5rX3RvX3Rlcm1fcGFnZSI6Im9uIiwic2VwYXJhdG9yIjoiIHwgIiwiY2F0ZWdvcnlfdHlwZSI6ImNhdGVnb3J5In19@” admin_label=”••• Cabeçalho de largura completa | CATEGORIA DO POST •••” _builder_version=”4.6.6″ _dynamic_attributes=”title” _module_preset=”default” title_level=”h5″ title_font=”Open Sans|||on|||||” title_font_size=”17px” subhead_font=”Open Sans||||||||” subhead_font_size=”17px” subhead_line_height=”0.8em” background_color=”#2D1E72″ width=”100%” max_width=”100%” custom_margin=”||||false|false” custom_padding=”3.2%||0px|15%|false|false” custom_padding_tablet=”” custom_padding_phone=”|||0%|false|false” custom_padding_last_edited=”on|phone” custom_css_title=”font-weight: 700;” custom_css_subtitle=”font-weight: 700;” global_module=”873″][/et_pb_fullwidth_header][et_pb_fullwidth_post_title categories=”off” comments=”off” featured_image=”off” text_color=”light” admin_label=”• Título da publicação de largura inteira | TITULO DO POST •” _builder_version=”4.6.6″ _module_preset=”default” title_font_size=”72px” meta_font_size=”15px” background_color=”#2d1e72″ width=”100%” custom_margin=”||||false|false” custom_padding=”50px||13%|15%|false|false” custom_padding_tablet=”” custom_padding_phone=”10px||13%|0%|false|false” custom_padding_last_edited=”on|phone” title_font_size_tablet=”58px” title_font_size_phone=”40px” title_font_size_last_edited=”on|tablet” custom_css_post_title=”font-weight: 700;” custom_css_post_meta=”font-weight: 700;”][/et_pb_fullwidth_post_title][/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.5.6″ _module_preset=”default” custom_margin=”0px||||false|false”][et_pb_row column_structure=”1_3,2_3″ module_class=”linha-projetos” _builder_version=”4.6.6″ _module_preset=”default” background_color=”#AC5EEB” max_width=”1200px” custom_margin=”||||false|false” custom_padding=”||||false|false” border_radii=”on|20px|20px|20px|20px”][et_pb_column type=”1_3″ _builder_version=”4.5.6″ _module_preset=”default” background_enable_color=”off” custom_css_main_element=”display: flex;||align-items: center;”][et_pb_image title_text=”Pages from OECD- measuring innovation new perspectives_45362740″ src_tablet=”” src_phone=”” src_last_edited=”on|desktop” admin_label=”• Imagem do post – IMAGEM •” _builder_version=”4.7.1″ _module_preset=”default” max_width=”65%” max_width_tablet=”30%” max_width_phone=”30%” max_width_last_edited=”on|phone” module_alignment=”right” custom_margin_tablet=”||||false|false” custom_margin_phone=”” custom_margin_last_edited=”on|tablet” custom_padding=”0px||0px||false|false” custom_padding_tablet=”3%||0px||false|false” custom_padding_phone=”3%||||false|false” custom_padding_last_edited=”on|desktop” module_alignment_tablet=”center” module_alignment_phone=”” module_alignment_last_edited=”on|desktop” global_module=”253″ saved_tabs=”all” src__hover_enabled=”on|desktop”][/et_pb_image][/et_pb_column][et_pb_column type=”2_3″ _builder_version=”4.5.6″ _module_preset=”default” background_enable_color=”off” custom_padding=”|10%|||false|false” custom_css_main_element=”display: flex;||align-items: center;”][et_pb_text admin_label=”• Texto do post – TEXTO •” _builder_version=”4.7.1″ _module_preset=”default” text_text_color=”#ffffff” text_font_size=”19px” header_text_color=”#ffffff” header_2_text_color=”#ffffff” header_3_text_color=”#ffffff” header_4_text_color=”#ffffff” header_5_text_color=”#ffffff” header_6_text_color=”#ffffff” max_width_tablet=”90%” max_width_phone=”” max_width_last_edited=”on|phone” custom_padding=”5%||5%||false|false” custom_padding_tablet=”2%||||false|false” custom_padding_phone=”” custom_padding_last_edited=”on|phone” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|phone” header_2_font_size_tablet=”” header_2_font_size_phone=”20px” header_2_font_size_last_edited=”on|phone” header_2_line_height_tablet=”1.4em” header_2_line_height_phone=”1.4em” header_2_line_height_last_edited=”on|phone” module_alignment_tablet=”right” module_alignment_phone=”” module_alignment_last_edited=”on|phone” custom_css_main_element=”line-height: 1.7em;” global_module=”251″ saved_tabs=”all”]
With the validation of the prototype in a relevant environment, we have reached TRL# 5 and will end the experimental development stage – ANEEL’s DE. At this stage, we begin to evaluate the efficacy, efficiency and safety of the GMO.
- Laboratory experiments to advance the understanding of GMO safety, assessing the possibility of horizontal transmission (non-reproductive, unintentional, to non-target species) of the CRISPR construct, a prerequisite of the WHO (Phase I) and CTNBIO guidelines;
- Laboratory experiments to advance understanding of the efficacy of the GMO, assessing the frequency of vertical transmission (reproductive, intentional) over 5 generations, as suggested by the WHO guidelines (Phase I). Also evaluate the occurrence of mutations in GMO mussels.
- Experiments in micro and mesocosms (controlled environment, contained, in the field) replicating the environment (same water and same species) of a reservoir, assessing by genotyping the possibility of horizontal transmission (non-reproductive, unintentional) of the CRISPR construct to other (cultivable) species in the aquatic trophic chain: bacteria, phyto- and zooplankton, other aquatic invertebrates and specifically molluscs, fish that eat mussels and fish that feed on other fish, as prerequisite of the WHO guidelines (Phase I and Phase II) and CTNBIO.
[/et_pb_text][/et_pb_column][/et_pb_row][et_pb_row admin_label=”• Linha •” _builder_version=”4.6.6″ _module_preset=”default” background_enable_color=”off” width=”70%” max_width=”1100px” custom_margin=”||||false|false” custom_padding=”||||false|false” custom_css_main_element=”display: flex;” global_module=”271″ collapsed=”off”][et_pb_column type=”4_4″ _builder_version=”4.5.6″ _module_preset=”default” background_enable_color=”off”][et_pb_post_nav in_same_term=”on” prev_text=”anterior” next_text=”próximo” admin_label=”• Navegação da postagem – BOTÕES ANTERIOR E PRÓXIMO •” _builder_version=”4.6.0″ _module_preset=”default” title_text_color=”#2D1E72″ title_font_size=”17px”][/et_pb_post_nav][/et_pb_column][/et_pb_row][/et_pb_section]